ERCC2

Gene

4 papers3 findings

  • 2 independent labs
  • Humans1
  • Animals2

Effects

2

Lifespan

downin mice1

1 study
  1. ERCC2 shortens lifespan in mice.

    AnimalsTTD mutation

    Premature aging in mice deficient in DNA repair and transcription

    Science (New York, N.Y.)11 Apr 2002

Sister chromatid exchange frequency

no changein humans1

1 study
  1. ERCC2 has no effect on sister chromatid exchange frequency in humans.

    Humans

    Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

    Carcinogenesis1 May 2000

More on Sister chromatid exchange frequency

Associations

1

Osteoporosis

upin mice1

1 study
  1. ERCC2 raises the risk of osteoporosis in mice.

    AnimalsTTD mutation

    Premature aging in mice deficient in DNA repair and transcription

    Science (New York, N.Y.)11 Apr 2002

More on Osteoporosis

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