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International Journal of Molecular SciencesCells·27 Aug

MCL1 Promotes Endothelial Senescence and Atherosclerosis via Glycolytic Reprogramming-Induced H4K12 Lactylation

Glycolysis
GSA 2024 AbstractCells·1 Jan

CROSSTALK BETWEEN HYALURONAN AND ITS REGULATORS AFFECTS AGING

Mechanisms

Related

  • Apoptosis1
  • CD441
  • CDKN1A1
  • Cellular senescence1
  • Extracellular matrix1
  • Extracellular matrix remodelling1
  • Glycolysis1
  • H4K12 lactylation1
  • HAS21
  • HAS2 and HAS3 mRNA1
  • HAS31
  • Histone modification and chromatin remodelling1
  • MCL11
  • PPP1R13L1
  • Senescence-associated secretory phenotype (SASP)1
  • TGF-β signalling1
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    Trials

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    Registered6 Oct 2026

    AKG and Brain Health in Aging

    Phase 2 · University of Oklahoma

    Registered2 Oct 2026

    Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

    Phase 1 · Vinmec Research Institute of Stem Cell and Gene Technology

    Registered7 Oct 2026

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