Sister chromatid exchange frequency

1. ERCC2 has no effect on sister chromatid exchange frequency in humans.

   “The polymorphism in ERCC2 was unrelated to SCE frequency or DNA adduct level.”

   Humans

   Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

   Carcinogenesis·1 May 2000

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1. XRCC1 is associated with sister chromatid exchange frequency in humans.

   “Mean SCE frequencies among current smokers who were homozygous carriers of the 399Gln allele in XRCC1 were greater than those in 399Arg/Arg current smokers.”

   Humansin current smokers

   Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells

   Carcinogenesis·1 May 2000

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