Cockayne syndrome

3 papers

Animals2

Funding

1 grant since 2024

National Institute of Neurological Disorders and StrokeUS$420.4k

Gene Therapy for Xeroderma Pigmentosum - Cockayne Syndrome.
National Institute of Neurological Disorders and StrokeUniversity of MinnesotaUS$420.4k2024–2027

Latest

Nature24 Aug

Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

Experiments in miceDietary restriction

Cell Metabolism4 Nov

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

Experiments in miceInterventions

Cell8 May

Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction

Experiments in wormsInterventions

Biochimie1 Nov

DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

ReviewDNA repair

Nature Genetics1 Sep

The Werner syndrome protein is a DNA helicase

Experiments in human cellsMechanisms