CRLS1

Gene1 paper3 findingsHGNC 16148MGI 1913836NCBI Gene 54675Taxon 9606

One mouse study reports that CRLS1 mediates fibre-type adaptations and reduces muscle atrophy and mortality in adult Crls1 knockout mice.

  • Animals1

Effects

3

Mortality

downin mice1

1 study
  1. CRLS1 decreases mortality in mice.

    Animalsin adult Crls1 knockout mice

    Cardiolipin decline drives muscle fiber shifts in mice · Nature aging · 29 Sep 2026

Muscle atrophy

downin mice1

1 study
  1. CRLS1 decreases muscle atrophy in mice.

    Animalsin adult Crls1 knockout mice

    Cardiolipin decline drives muscle fiber shifts in mice · Nature aging · 29 Sep 2026

Fiber-type adaptations

mediatesin mice1

1 study
  1. CRLS1 mediates fiber-type adaptations in mice.

    Animalsin mice

    Cardiolipin decline drives muscle fiber shifts in mice · Nature aging · 29 Sep 2026

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Nature AgingAnimals

Cardiolipin decline drives muscle fiber shifts in mice

Deleting cardiolipin synthase in young mice induced age-like fiber shifts, while restoring its expression reversed atrophy and rescued premature…Deleting cardiolipin synthase in young mice induced age-like fiber shifts, while restoring its expression reversed atrophy and rescued premature mortality.