CPEB1
- 1 lab in 1 country
- Funders: Barcelona Institute of Science and Technology and 7 more
- Animals1
- Cells1
Effects
2Translation phenotypes of old oocytes
downin mouse cells1
1 study
Translation phenotypes of old oocytes
downin mouse cells1
CPEB1 prevents translation phenotypes of old oocytes in mouse cells.
“Oocyte-specific Cpeb1 haploinsufficiency in young oocytes recapitulates all the translation phenotypes of old oocytes.”
CellsCpeb1 haploinsufficiencyoocyte
CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging
Nature communicationsJan 26, 2023
CCNB1
downin mouse cells1
1 study
CCNB1
downin mouse cells1
CPEB1 inhibits CCNB1 in mouse cells.
“This decrease causes de-repression of Ccnb1 translation in quiescent oocytes, premature CDK1 activation, and accelerated reentry into meiosis.”
CellsCpeb1 haploinsufficiencyoocyte
CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging
Nature communicationsJan 26, 2023
Latest
Nature Communications
CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging
Experiments in animalsMechanisms
Genes & Development
CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation
Experiments in human cellsOxidative phosphorylation