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CHA4

Gene

1 paper1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: European Molecular Biology Organization and 4 more
  • 1 of 1 finding with company ties
  • Cells1

Effects

1

Protein aggregates

downin yeast cells1

1 study

  1. CHA4 decreases protein aggregates in yeast cells.

    “deletion of serine-dependent transcriptional activator, CHA4, resulted in increased aggregation of endogenous proteins”

    Cellsdeletion of CHA4

    Perturbations in L-serine metabolism regulate protein quality control through the sensor of the retrograde response pathway RTG2 in Saccharomyces cerevisiae

    The Journal of biological chemistry31 May 2025

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