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CENPA

Gene

3 papers1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 1 more
  • Animals1
  • Cells1
  • In silico1

Effects

1

Premature separation of sister chromatids

downin cells1

1 study

  1. CENPA inhibits premature separation of sister chromatids in cells.

    “we identified the centromeric protein CENP-A as a new factor whose aging-like depletion causes a dramatic rise in premature separation of sister chromatids.”

    Cellstargeted protein degradationegg

    A versatile cohesion manipulation system reveals CENP-A dysfunction accelerates female reproductive age-related egg aneuploidy

    bioRxiv : the preprint server for biology27 Feb 2025Preprint

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