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BgILP2

Gene

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 3 more
  • Model organisms1

Effects

3

Lifespan

downin B. germanica1

1 study

  1. BgILP2 shortens lifespan in B. germanica.

    “repression of BgILP2 led to elevated circulating sugar levels, reduced lipid and glycogen storage, and a modest increase in the lifespan of female cockroaches”

    Model organismsunder low-nutrient conditionsfemales

    An ovarian insulin-like peptide specifically regulates energy allocation and oocyte development in nutrition-restricted cockroaches

    BMC biology28 Jul 2025

Oocyte development

is required forin B. germanica1

1 study

  1. BgILP2 is required for oocyte development in B. germanica.

    “ultimately leading to delayed oocyte development under nutrient restriction”

    Model organismsunder nutrient restrictionfemales

    An ovarian insulin-like peptide specifically regulates energy allocation and oocyte development in nutrition-restricted cockroaches

    BMC biology28 Jul 2025

Vitellogenesis

is required forin B. germanica1

1 study

  1. BgILP2 is required for vitellogenesis in B. germanica.

    “Repression of BgILP2 impairs vitellogenesis in the fat body”

    Model organismsunder nutrient restrictionfemales

    An ovarian insulin-like peptide specifically regulates energy allocation and oocyte development in nutrition-restricted cockroaches

    BMC biology28 Jul 2025

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