Type A aortic dissection

Disease

1 paper4 findings

  • In silico1

Effects

3

Macrophage content

upin silico1

1 study
  1. Type A aortic dissection increases macrophage content in silico.

    “an increase in NK cells and macrophages.”

    In silicoin AAD tissues compared with normal tissuesaorta

    The role of senescence-related hub genes correlating with immune infiltration in type A aortic dissection: Novel insights based on bioinformatic analysis

    PloS one25 Jun 2025

More on Macrophage content

NK cells

upin silico1

1 study
  1. Type A aortic dissection increases NK cells in silico.

    “Compared with normal tissues, AAD tissues exhibited a significant decrease in CD8 T cells and an increase in NK cells and macrophages.”

    In silicoin AAD tissues compared with normal tissuesaorta

    The role of senescence-related hub genes correlating with immune infiltration in type A aortic dissection: Novel insights based on bioinformatic analysis

    PloS one25 Jun 2025

More on NK cells

CD8+ T cell

downin silico1

1 study
  1. Type A aortic dissection decreases CD8+ T cell in silico.

    “Compared with normal tissues, AAD tissues exhibited a significant decrease in CD8 T cells”

    In silicoin AAD tissues compared with normal tissuesaorta

    The role of senescence-related hub genes correlating with immune infiltration in type A aortic dissection: Novel insights based on bioinformatic analysis

    PloS one25 Jun 2025

More on CD8+ T cell

Associations

1

CHEK1

upin silico1

1 study
  1. CHEK1 predicts type A aortic dissection in silico (AUC > 0.9).

    “three diagnostic genes with high Area Under the Curve (AUC > 0.9) were identified: CHEK1, FOXM1, BRCA1.”

    In silicoROC curve analysis for AAD diagnosis

    The role of senescence-related hub genes correlating with immune infiltration in type A aortic dissection: Novel insights based on bioinformatic analysis

    PloS one25 Jun 2025

More on CHEK1

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 1Sep 2026: 0Oct 2026: 01 in 12 months