AgingResearch.NewsJoin free

MAD2L1

Gene

2 papers1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development and 1 more
  • Animals1
  • In silico1

Upstream

1

Aurkb cKO

downin mice1

1 study

  1. Aurkb cKO decreases MAD2L1 in mice.

    “We show that the increased desensitization of the SAC is driven by reduced expression of MAD2, ZW10 and Securin proteins, key contributors to the SAC response pathway.”

    Animalsin Aurkb cKO oocytesoocytefemales

    Age-dependent integrity of the meiotic spindle assembly checkpoint in females requires Aurora kinase B

    Aging cell26 Oct 2021

Latest

Related