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Risk of coronary artery disease, peripheral artery disease, aortic stenosis, and abdominal aortic aneurysm

There is 1 paper on risk of coronary artery disease, peripheral artery disease, aortic stenosis, and abdominal aortic aneurysm in aging research: 1 observational study in people. The newest story, Nov 9, 2026: “Genetic study links two proteins to different cardiovascular risks”.

Disease

1 paper studies it2 findings

1 new paper in 30 daysSee all 1 papers on risk of coronary artery disease, peripheral artery disease, aortic stenosis, and abdominal aortic aneurysm

“Genetically-proxied ANGPTL4 inhibition and LPL enhancement were both significantly associated with lower risk of CAD, PAD, AS, and AAA.”
Genetic Reduction in Angiopoietin-Like Proteins 3 and 4 Exerts Distinct Effects on Cardiovascular Disease Risk Through Differential Enhancement of Lipase ActivitiesAHA Scientific Sessions 2026 abstract2026doi:10.1161/circ.154.suppl_1.18414
  • Humans1

Associations

2

LPL

downin humans1

1 study

  1. LPL is associated with risk of coronary artery disease, peripheral artery disease, aortic stenosis, and abdominal aortic aneurysm in humans (Genetically proxied LPL enhancement).

    “Genetically-proxied ANGPTL4 inhibition and LPL enhancement were both significantly associated with lower risk of CAD, PAD, AS, and AAA.”

    HumansGenetically proxied LPL enhancement

    Genetic study links two proteins to different cardiovascular risks

    AHA Scientific Sessions 2026 abstract

More on LPL

ANGPTL4

downin humans1

1 study

  1. ANGPTL4 is associated with risk of coronary artery disease, peripheral artery disease, aortic stenosis, and abdominal aortic aneurysm in humans (Genetically proxied ANGPTL4 inhibition).

    “Genetically-proxied ANGPTL4 inhibition and LPL enhancement were both significantly associated with lower risk of CAD, PAD, AS, and AAA.”

    HumansGenetically proxied ANGPTL4 inhibition

    Genetic study links two proteins to different cardiovascular risks

    AHA Scientific Sessions 2026 abstract

More on ANGPTL4

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AHA Scientific Sessions 2026 Abstract

Genetic study links two proteins to different cardiovascular risks

Human genetic analyses linked lower activity of one fat-regulating protein to lower risks of four cardiovascular diseases, while a related protein showed little…Human genetic analyses linked lower activity of one fat-regulating protein to lower risks of four cardiovascular diseases, while a related protein showed little association with three.

Mendelian randomizationMechanisms
Paper

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