Premature ovarian ageing

Disease

1 paper1 finding

  • Animals1

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HMGCS2

downin mice1

1 study
  1. HMGCS2 protects against premature ovarian ageing in mice.

    “Hmgcs2 deficiency enhances follicle apoptosis and thus decreases the size of the primordial follicle pool and leads to premature ovarian ageing (POA)”

    Animalsshown by Hmgcs2 deficiencyovary

    The neonatal ketone body is important for primordial follicle pool formation and regulates ovarian ageing in mice

    Life metabolism11 Aug 2022

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