Premature aging diseases
2 papers
Latest
4 in 12 monthsAging Medicine (Milton (N.S.W))
Insights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research
CommentaryMechanisms
Journal of Bone and Mineral Research
Lonafarnib clinical trials demonstrate uncoupling of the muscle-bone unit in Hutchinson-Gilford Progeria Syndrome
Non-randomised trial in peopleProgeria
Life Science Alliance
The unfolded protein response in progeria arteries originates from non-endothelial cell types
Experiments in miceER unfolded protein response
Nature Communications
NAD⁺ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Experiments in wormsInterventions
Ageing Research Reviews
Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations
ReviewRNA splicing
Histochemistry and Cell Biology
Molecular insights into the premature aging disease progeria
ReviewLMNA
Nature
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
Experiments in human cellsLMNA
PNAS
Telomere dysfunction as a cause of genomic instability in Werner syndrome
Experiments in human cellsTelomerase and telomere maintenance