Alzheimer's & Dementia
Spinal fluid fats linked to later cognitive impairment
An observational study followed cognitively unimpaired older adults and found that specific spinal fluid fats improved predictions of later cognitive impairment.An observational study followed cognitively unimpaired older adults and found that specific spinal fluid fats improved predictions of later cognitive impairment.
Cohort · 270 peopleMild cognitive impairment
Who was studied270 cognitively unimpaired older adults, median 7.8 years
What changedRisk of cognitive impairment was lower with higher spinal fluid TAG(C49:6) (HR = 0.63)
The catchSample collection timing was not standardized, which may have influenced measured lipid profiles