Pakistan Armed Forces Medical Journal·Sep 30Effects of Post-Operative Cognitive Dysfunction (Pocd) After General Anesthesia In Geriatric PatientsCohort study of 330 peoplePostoperative cognitive dysfunctionPaper
Journal of Cellular and Molecular Medicine·Aug 11PRKCD Orchestrates Sevoflurane-Induced Cognitive Dysfunction in Aged Rats by Regulating PINK1/PRKN Mitophagy PathwayExperiments in ratsMitophagyPaper
Archives of Biochemistry and Biophysics·May 30Thiolutin ameliorates postoperative cognitive dysfunction induced by intestinal ischemia-reperfusion in aged mice: a potential role for modulation of the BRCC3/NLRP3 axisExperiments in micePostoperative cognitive dysfunctionPaper
Physiology·May 1Voluntary exercise prior to surgery mitigates post-operative cognitive dysfunction and enhances hippocampal mitochondrial respiration in 3xTg-AD miceExperiments in miceExercisePaper
World Journal of Gastrointestinal Pharmacology and Therapeutics·Mar 11Gut-brain axis and post-operative cognitive dysfunction: A multifactorial perspective on microbiota, inflammation, and cognitive healthReviewMicrobiome compositionPaper
Journal of Neuroinflammation·Feb 12FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged miceExperiments in miceLipid and ceramide metabolismPaper
International Journal of Molecular Sciences·Dec 11Post-Operative Delirium in Elderly Patients: A Narrative ReviewReviewPostoperative deliriumPaper
Immunity & Ageing·Aug 23Systemic inflammation as a central player in the initiation and development of Alzheimer's diseaseReviewInflammationPaper
JAR Life·Mar 6Pre-surgical memory impairment is associated with risk of postoperative cognitive dysfunction in a large geriatric cohortCohort study of 590 peoplePostoperative cognitive dysfunctionPaper
BMC Anesthesiology·Oct 9The association of pre-operative biomarkers of endothelial dysfunction with the risk of post-operative neurocognitive disorders: results from the BioCog studyCohort study of 788 peoplePerioperative neurocognitive disorderPaper
Journal of Clinical Medicine·Sep 28Association of Atrial Fibrillation and Cognitive Dysfunction: A Comprehensive Narrative Review of Current Understanding and Recent UpdatesReviewMechanismsPaper
European Geriatric Medicine·Aug 12The effect of pre-operative exercise training on post-operative cognitive function: a systematic reviewSystematic review of randomized trialsExercisePaper
Experimental and Therapeutic Medicine·Jul 15Propofol total intravenous anesthesia vs. sevoflurane inhalation anesthesia: Effects on post‑operative cognitive dysfunction and inflammation in geriatric patients undergoing laparoscopic surgeryNon-randomized trial in 197 peoplePostoperative cognitive dysfunctionPaper
Frontiers in Aging Neuroscience·Jun 24Impact of butorphanol versus sufentanil on postoperative cognition and inflammation in elderly: a pilot studyRandomized trial in 114 peopleInterventionsPaper
International Immunopharmacology·Mar 4The activation of RARα prevents surgery-induced cognitive impairments via the inhibition of neuroinflammation and the restoration of synaptic proteins in elderly miceExperiments in miceInterventionsPaper
Brain, Behavior, and Immunity·Dec 26Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementationExperiments in animalsInterventionsPaper
Cureus·Nov 7Post-Operative Cognitive Dysfunction in Elderly Patients Receiving Propofol Sedation for Gastrointestinal Endoscopies: An Observational Study Utilizing Processed ElectroencephalographyCohort study of 400 peoplePostoperative cognitive dysfunctionPaper
Pacing and Clinical Electrophysiology·Nov 27Changes in cognitive function after thoracoscopic and catheter ablation for atrial fibrillationTrial in peopleInterventionsPaper
Brain Research Bulletin·Jan 15Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signalingExperiments in miceCognitive dysfunctionPaper
American Journal of Translational Research·Nov 18The effect of dexmedetomidine combined with epidural anesthesia on post-operative cognitive dysfunction in elderly patients after orthopedic surgeryRandomized trial in 187 peoplePostoperative cognitive dysfunctionPaper
Trials·Oct 11Efficiency of donepezil in elderly patients undergoing orthopaedic surgery due to underlying post-operative cognitive dysfunction: study protocol for a multicentre randomised controlled trialStudy protocolDonepezilPaper
Indian Journal of Anaesthesia·Jan 14Substitution of propofol for dexmedetomidine in the anaesthetic regimen does not ameliorate the post-operative cognitive decline in elderly patientsRandomized trial in 80 peopleInterventionsPaper
Research Square·Dec 18Paracetamol (acetaminophen) as potential first-choice analgesic in post-operative cognitive decline (POCD): Behavioral and molecular evidence in a middle-aged rat modelPreprint: experiments in ratsInterventionsPaper
Medical Science Monitor·Feb 16Impact of Sevoflurane Versus Propofol Anesthesia on Post-Operative Cognitive Dysfunction in Elderly Cancer Patients: A Double-Blinded Randomized Controlled TrialTrial in peopleInterventionsPaper
Acta Anaesthesiologica Scandinavica·Nov 13Association of global DNA hypomethylation with post-operative cognitive dysfunction in elderly patients undergoing hip surgeryStudy in peopleBiomarkersPaper
Experimental and Therapeutic Medicine·Oct 24Characterization of DNA hydroxymethylation in the hypothalamus of elderly mice with post-operative cognitive dysfunctionExperiments in animalsMechanismsPaper
Biomedicine & Pharmacotherapy·Sep 13Compound K attenuated hepatectomy-induced post-operative cognitive dysfunction in aged mice via LXRα activationExperiments in animalsInterventionsPaper
Experimental and Therapeutic Medicine·Aug 1Effects of different analgesia regimens on early post-operative cognitive dysfunction in elderly patients undergoing radical resection of cervical carcinomaNon-randomized trial in 74 peoplePostoperative cognitive dysfunctionPaper
International Immunopharmacology·Mar 17Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-κB/MAPKs pathway and promoting IL-10 expression in aged miceExperiments in micePostoperative cognitive dysfunctionPaper
Biomedicine & Pharmacotherapy·Sep 5Thalidomide alleviates postoperative pain and spatial memory deficit in aged ratsExperiments in ratsInterventionsPaper