Osteosarcopenic obesity

1. Osteosarcopenic obesity impairs cognitive function in humans.

   “Increasing OSO burden (from 0 to 3 conditions) was associated with progressively greater frailty and cognitive decline.”

   Humansup to 14 years

   Osteosarcopenic obesity and the progression of physical frailty, cognition function, and mental health: First longitudinal evidence from ELSA

   The journal of nutrition, health & aging·27 Nov 2025

1. Osteosarcopenic obesity increases physical frailty in humans.

   “Increasing OSO burden (from 0 to 3 conditions) was associated with progressively greater frailty and cognitive decline.”

   Humansup to 14 years

   Osteosarcopenic obesity and the progression of physical frailty, cognition function, and mental health: First longitudinal evidence from ELSA

   The journal of nutrition, health & aging·27 Nov 2025

1. Osteosarcopenic obesity is associated with fragility fractures in humans.

   “This multifaced deleterious scenario is strongly correlated with an increasing risk of fragility fractures, falls, functional and metabolic decline, all of which contribute to higher morbidity and mortality.”

   Review

   Vitamin D in the elderly: the phil-rouge in preventing bone, muscle and adipose deterioration?

   Archives of endocrinology and metabolism·3 Dec 2025

1. Vitamin D is associated with osteosarcopenic obesity in humans.

   “vitamin D deficiency in the elderly has been consistently associated with progressive bone deterioration and muscle and adipose dysfunctions, concurring to the occurrence of the osteosarcopenic obese phenotype.”

   Review

   Vitamin D in the elderly: the phil-rouge in preventing bone, muscle and adipose deterioration?

   Archives of endocrinology and metabolism·3 Dec 2025

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