Myeloid neoplasia

Clearing senescent niche cells limits clonal haematopoiesis in mice

Mutant blood cells induced stromal senescence, while depleting senescent non-haematopoietic cells reduced clonal burden and delayed progression to…Mutant blood cells induced stromal senescence, while depleting senescent non-haematopoietic cells reduced clonal burden and delayed progression to myeloid neoplasia in mice.