1 paper1 finding
High-risk clonal haematopoiesis or future myeloid neoplasia
upin humans1
PRISM predicts high-risk clonal haematopoiesis or future myeloid neoplasia in humans (AUC 0.89 (95% CI 0.85–0.93)).
“Validation of PRISM revealed an area under the curve of 0.89 (95% CI 0.85-0.93) in the UK Biobank test cohort”
HumansUK Biobank internal test cohortn = 92,316
Blood counts help flag high-risk blood cancer precursors
EClinicalMedicine22 Sep 2026
More on High-risk clonal haematopoiesis or future myeloid neoplasia
The model categorised all high-risk cases as positive and pre-classified 40% of low-risk cases and 55% of negative cases as negative.The model categorised all high-risk cases as positive and pre-classified 40% of low-risk cases and 55% of negative cases as negative.
Over a median 11.45 years, major heart and brain blood-vessel events affected 49.40% with both conditions, versus 17.00% without sleep apnoea and with normal lung…Over a median 11.45 years, major heart and brain blood-vessel events affected 49.40% with both conditions, versus 17.00% without sleep apnoea and with normal lung function.