3 papers
Company1 trialPhase 2168 people
Company1 trialPhase 2120 people
Esbjerg Hospital - University Hospital of Southern Denmark
1 trialPhase 464 people
1 trialPhase 420 people
1 trialPhase 2/320 people
Vanderbilt University Medical Center
1 trialPhase 290 people
1 trialPhase 210 people
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$4.1mNational Institute on AgingUS$3.5mVeterans Affairs
National Institute on AgingRidgeline TherapeuticsUS$1.3m2025–2027
The role of cellular senescence in skeletal muscle loss and dysfunction
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUniversity of Alabama at BirminghamUS$223.2k2024–2027
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUniversity of Texas at AustinUS$925.7k2022–2027
Determinants and Outcomes of Age-related Muscle Loss
National Institute on AgingHebrew Rehabilitation Center for AgedUS$631.1k2021–2027
Combining Prostaglandin E2 Modulation and Rehabilitation for Treatment of Volumetric Muscle Loss
Veterans AffairsVeterans Admin Palo Alto Health Care Sys2024–2027
European CommissionThe Chancellor Masters and Scholars of the University of Cambridge€454.1k2026–2029
An Intelligent Biorobot for the Regenerative Rehabilitation of Volumetric Muscle Loss Defects
National Institute of Arthritis and Musculoskeletal and Skin DiseasesCleveland State UniversityUS$616.3k2025–2030
Suturable bioprinted vascularized muscle constructs for treatment of skeletal muscle loss
National Institute of Arthritis and Musculoskeletal and Skin DiseasesBrigham and Women's HospitalUS$488.9k2021–2027
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUniversity of Arkansas at FayettevilleUS$434.8k2024–2027
Overfeeding young mice damaged gut microbes, impaired muscle cell energy production, and worsened age-related muscle wasting in later life.Overfeeding young mice damaged gut microbes, impaired muscle cell energy production, and worsened age-related muscle wasting in later life.
Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.
People with intramuscular fat fractions above 10% showed significantly lower paraspinal muscle mass and strength than those with levels below 5%.People with intramuscular fat fractions above 10% showed significantly lower paraspinal muscle mass and strength than those with levels below 5%.
Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.Delivering miR-193b-3p improved muscle repair in injured mice and targeted a protein elevated in sarcopenic human tissue.