Multivessel coronary artery disease

1. Lipoprotein is associated with multivessel coronary artery disease in humans (OR 1.45, 95% CI 1.04–2.01; p = 0.027).

   “In secondary prevention, Lp(a) ≥175 nmol/L was associated with multivessel disease after multivariable adjustment for age, sex, LDLc, and statin treatment”

   HumansSecondary prevention after non-fatal acute coronary syndrome; lipoprotein(a) ≥175 nmol/L; adjusted for age, sex, LDLc, and statin treatmentn = 788

   Lipoprotein(a) epidemiology and role in secondary and primary-and-a-half cardiovascular prevention: From subclinical atherosclerosis to coronary events

   American journal of preventive cardiology·Jan 23, 2026

2. Lipoprotein is associated with multivessel coronary artery disease in humans (adjusted OR: 1.43 [per 100 nmol/L]; 95% CI: 1.04-1.96; P = 0.028).

   “In multivariable analysis, Lp(a) was associated with multivessel CAD (adjusted OR: 1.43 [per 100 nmol/L]; 95% CI: 1.04-1.96; P = 0.028)”

   Humansper 100 nmol/L

   Lipoprotein(a) and the Early Diagnosis, Complexity, and Extent of Coronary Artery Disease and Myocardial Infarction

   JACC. Advances·Jan 19, 2026

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1. Older age is associated with multivessel coronary artery disease in humans (acute myocardial infarction) (75.4% vs 57.9%; p < 0.05).

   “the proportion remained significantly higher in patients > 45 years (75.4% vs 57.9%; p < 0.05), indicating more diffuse coronary involvement with advancing age.”

   Humansacute myocardial infarctioncoronary artery

   Characteristics of Coronary Artery Lesions in Patients with Acute Myocardial Infarction Under 45 Years of Age

   Tạp chí Phẫu thuật và Tim mạch và Lồng ngực Việt Nam·Oct 28, 2026

1. Postmenopause is associated with multivessel coronary artery disease in acute coronary syndrome patients (72.34% vs 40.21%).

   “Multivessel lesions were more commonly noted on angiography in the postmenopausal group than in the premenopausal group (40.21% vs 72.34%; P < 0.0001).”

   Humansin acute coronary syndrome patientscoronary arteryfemalesn = 191

   Differences in Culprit Lesions Between Premenopausal and Postmenopausal Women With Acute Coronary Syndrome: An Optical Coherence Tomography Study

   The Canadian journal of cardiology·Oct 19, 2021

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