HLife
Mice lacking a lung protein developed worse lung scarring
In experiments with male mice, chemically induced lung scarring persisted at 56 days without the protein but had nearly resolved in mice with it.In experiments with male mice, chemically induced lung scarring persisted at 56 days without the protein but had nearly resolved in mice with it.
Mouse studyLung
Who was studiedMale mice, 56 days, against bleomycin-treated wild-type mice
What changedMice lacking ISM1 developed worse lung scarring after bleomycin treatment than wild-type mice
The catchNo ISM1 replacement experiment assessed whether restoring the protein reverses excess lung scarring