An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.
In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.
In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.