Hepatitis

Disease

2 papers

  • Humans2

Trial sponsors

Funding

2 grants since 2025

National Cancer InstituteUS$547.9kEuropean Commission€209.5k

Latest

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Ecotoxicology and Environmental Safety

Tributyl phosphate caused signs of liver aging in rats

An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.

Experiments in ratsMechanisms
bioRxiv

Caloric restriction delays cancer wasting in mice

In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.In a mouse model of lung cancer, restricting food before tumour induction preserved lean mass and prolonged survival where targeting individual candidate factors failed.

Preprint: experiments in miceDietary restriction
Journal of Cellular Physiology

Sestrin1 protects aging livers and aids exercise in mice

In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.In aged mice, lacking Sestrin1 worsened liver cell senescence and fat buildup, and the protein proved indispensable for the liver benefits of exercise.

Experiments in miceExercise