Decompensated alcoholic cirrhosis

Disease

1 paper studies it2 findings

  • Humans1

Effects

2

Oxidative phosphorylation

downin human cells1

1 study
  1. Decompensated alcoholic cirrhosis impairs oxidative phosphorylation in human cells.

    “cBM-MSCs also showed a significant impairment in Oxidative phosphorylation (OXPHOS) due to mitochondrial dysfunction”

    Cellsin decompensated alcoholic cirrhosis patientsbone marrow

    Defects in energy metabolism are associated with functional exhaustion of bone marrow mesenchymal stem cells in cirrhosis

    American journal of stem cells

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Glycolysis

downin human cells1

1 study
  1. Decompensated alcoholic cirrhosis decreases glycolysis in human cells (P=0.002).

    “cBM-MSCs showed a significant defect in glycolysis due to insulin resistance and poor glucose uptake (P=0.002).”

    Cellsin decompensated alcoholic cirrhosis patientsbone marrow

    Defects in energy metabolism are associated with functional exhaustion of bone marrow mesenchymal stem cells in cirrhosis

    American journal of stem cells

More on Glycolysis

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