Crescentic glomerulonephritis

1. Caloric restriction decreases crescentic glomerulonephritis in mice (>5-week delay to heavy proteinuria, >4-week delay to hematuria).

   “Progression to severe glomerular pathology was delayed among Group C mice, with more than a 5-week delay to heavy proteinuria (>100 mg/dl), a >4-week delay to hematuria”

   AnimalsSCG/Kj micekidney32% fewer caloriesn = 113

   Calorie restriction delays the crescentic glomerulonephritis of SCG/Kj mice

   Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·1 Jul 1998

More on Caloric restriction