Central nervous system decline

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Communications Biology5 Jun

Cardiac-derived extracellular vesicles carrying miR-4433b-3p accelerate cognitive decline and brain aging by suppressing TP53INP2-mediated neuronal autophagy in mice

Study in peopleAutophagy

Acta Biochimica et Biophysica Sinica21 Mar

Novel small-molecule positive allosteric modulator 1 with blood-brain barrier penetration activity exerts anti-cellular senescence effects via the PAC1-R/YY1/SIRT6 pathway

Experiments in rat cellsInterventions

Journal of Neurochemistry27 Jan

From Neuron-Centric to Glia-Centric: How Aging Glial Networks Drive Neurodegenerative Disease

ReviewMechanisms