Papers on brain degeneration

55 papers1 new in 30 days

Tuesday, November 3

Frontiers in NeurologyNov 3

Association between white-matter lesion volume and heart-rate variability: A comparison of T1w, T1w+T2w and T1w+FLAIR-based segmentations using FreeSurfer SAMSEG

Accepted, not yet published: cross-sectional study in peopleHeart rate variability

Paper

Thursday, August 27

bioRxivAug 27

A conserved serotonin receptor pathway is a druggable modifier of Tau pathology, neural circuit formation and neurodegeneration

Neuronal expression of human TauP301L in Drosophila induces Tau hyperphosphorylation.

Preprint: experiments in fliesMechanisms

Paper

Tuesday, June 30

Faktori Eksperimental Noi Evolucii OrganizmivJun 30

Effects of high concentration spermidine supplementation during larval feeding in D. melanogaster swiss cheese mutants

Experiments in fliesSpermidine

Paper

Monday, March 30

Brain CommunicationsMar 30

Synergistic effects of cerebral small vessel disease burden and plasma phosphorylated tau 181 on white matter microstructure and cognition in a Chinese cohort

Cohort study of 375 peopleMechanisms

Paper

Saturday, March 28

Journal of Ophthalmology and Advance ResearchMar 28

The Retina as a Bridge to the Brain: Shared Neurodegenerative Mechanisms and Therapeutic Perspectives

ReviewEye

Paper

Wednesday, December 24

Brain SciencesDec 24

Sex-Specific Impact of Metabolic Syndrome on Brain Structures Vulnerable to Alzheimer's Disease: A Cross-Sectional Study in a Brazilian Cohort

Cross-sectional study of 500 peopleMetabolic syndrome

Paper

Monday, December 22

bioRxivDec 22

Unveiling the secrets of brain resilience: Multimodal neuroimaging insights into Neural dynamics and neuroprotection in ageing

Preprint: cross-sectional study in peopleMechanisms

Paper

Friday, December 12

Progress in Biomedical EngineeringDec 12

3D Bioprinting cell-laden bioinks for engineering neural tissues and potential models for Parkinson's disease

ReviewInterventions

Paper

Wednesday, November 19

bioRxivNov 19

Association between white-matter lesion volume and heart-rate variability: A comparison of T1, T1-T2 and T1-FLAIR-based segmentations using FreeSurfer SAMSEG

Preprint: computational studyHeart rate variability

Paper

Sunday, December 29

Alzheimer's & DementiaDec 29

Choroid plexus cysts on 7T MRI: Relationship to aging and neurodegenerative diseases

Cross-sectional study in peopleNeurodegenerative disease

Paper

Sunday, December 1

Biological Psychiatry Cognitive Neuroscience and NeuroimagingDec 1

Metabolic Status Modulates Global and Local Brain Age Estimates in Overweight and Obese Adults

Cohort study of 114 peopleOverweight

Paper

Thursday, November 28

Aging CellNov 28

Epigenetic age acceleration predicts subject-specific white matter degeneration in the human brain

Cohort study of 98 peopleGrimAge

Paper

Sunday, October 13

Age and AgeingOct 13

Influence of intergenerational social mobility on brain structure and global cognition: findings from the Whitehall II study across 20 years

Cohort study of 771 peoplePopulations

Paper

Saturday, July 27

International Journal of Molecular SciencesJul 27

The Inflammasome Adaptor Protein ASC in Plasma as a Biomarker of Early Cognitive Changes

Cohort study in peopleBiomarkers

Paper

Thursday, May 23

Neurobiology of AgingMay 23

Multiscale brain age prediction reveals region-specific accelerated brain aging in Parkinson's disease

Case-control study of 1,240 peopleBrain age

Paper

Monday, May 6

Neurobiology of DiseaseMay 6

Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model

Experiments in miceMechanisms

Paper

Tuesday, January 2

bioRxivJan 2

Cognitive and molecular characterization of the Ts66Yah murine model of Down syndrome: deepening on hippocampal changes associated with genotype and aging

Preprint: experiments in miceMechanisms

Paper

Tuesday, September 19

Journal of NeuroradiologySep 19

Predicting brain age gap with radiomics and automl: A Promising approach for age-Related brain degeneration biomarkers

Computational studyBrain age gap

Paper

Friday, August 18

Aging CellAug 18

Heterochromatic silencing of immune-related genes in glia is required for BBB integrity and normal lifespan in drosophila

Experiments in fliesImmune response

Paper

Monday, August 14

Frontiers in PhysiologyAug 14

Exploring the therapeutic potential of the mitochondrial transfer-associated enzymatic machinery in brain degeneration

ReviewMitochondrion

Paper

Monday, July 24

Ageing Research ReviewsJul 24

Turquoise killifish: A natural model of age-dependent brain degeneration

Experiments in killifishMechanisms

Paper

Friday, June 16

Molecular Medicine ReportsJun 16

Age‑related brainstem degeneration through microRNA modulation in mice

Experiments in miceMechanisms

Paper

Wednesday, March 29

Aging CellMar 29

Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation

Experiments in miceMechanisms

Paper

Thursday, March 16

Alzheimer's Research & TherapyMar 16

Attenuation of Alzheimer's brain pathology in 5XFAD mice by PTH₁₋₃₄, a peptide of parathyroid hormone

Experiments in miceAlzheimer's disease

Paper

Saturday, September 3

International Journal of PsychophysiologySep 3

Electroencephalographic hallmarks of Alzheimer's disease

ReviewAlzheimer's disease

Paper

Thursday, May 19

GeroScienceMay 19

A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer's disease

Cohort study of 25 peopleAlzheimer's disease

Paper

Wednesday, May 18

Brain Structure & FunctionMay 18

Aberrant topological organization and age-related differences in the human connectome in subjective cognitive decline by using regional morphology from magnetic resonance imaging

Cross-sectional study of 77 peopleMechanisms

Paper

Wednesday, March 23

Experimental GerontologyMar 23

D-galactose-induced aging in rats - The effect of metformin on bioenergetics of brain, skeletal muscle and liver

Experiments in ratsMetformin

Paper

Thursday, February 3

arXivFeb 3

Network resilience in the aging brain

Preprint: cohort study of 63 peopleMechanisms

Paper

Tuesday, November 2

Stem Cells Translational MedicineNov 2

Neuronal cell-based medicines from pluripotent stem cells: Development, production, and preclinical assessment

ReviewInterventions

Paper