Bone marrow obesity

Disease

1 paper1 finding

  • Humans1

Interventions

1

Irisin

downin mice1

1 study
  1. Irisin decreases bone marrow obesity in mice.

    “irisin inhibited adipogenic differentiation of BMMSCs in vitro and reduced bone loss and abnormal bone marrow obesity in ovariectomized (OVX) mice.”

    Animalsovariectomized micebone marrow

    Irisin inhibits adipogenic differentiation of bone marrow mesenchymal stem cells through the SIRT1/RANBP2/FTO signaling axis and protects against osteoporosis

    Cell death discovery25 Feb 2026

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