Nature Neuroscience
Boosting a secreted enzyme protected memory in aging mice
Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.Experiments in mice suggested that an enzyme released by nerve cells helps compensate for age-related brain changes and preserve memory.
Mouse studyMechanisms
Who was studiedAged male mice, 5 weeks, against aged mice receiving control virus
What changedAged mice with boosted Pla2g2f retained spatial memory, while aged control mice had impaired memory
The catchThe aged-mouse memory benefit was assessed just 5 weeks after injection