Age-associated immune dysfunction

There is 1 paper on age-associated immune dysfunction in aging research: none in people yet, 1 in animals. The newest story, Oct 30, 2026: “Older human lymph nodes show signs of immune cell dysfunction”.

Disease

1 paper studies it17 more mention it

2 new papers in 30 daysSee all 18

  • Animals1

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Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 1Aug 2026: 1Sep 2026: 1Oct 2026: 1Nov 2026: 17 papers in 12 months
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Inhibiting brain neurons restored immune cell production in aged mice

In experiments in aged mice, inhibiting specific brain neurons or deleting a gene involved in inflammatory signaling improved the response to a flu vaccine.In experiments in aged mice, inhibiting specific brain neurons or deleting a gene involved in inflammatory signaling improved the response to a flu vaccine.

Preprint: mouse studyBlood and immune system
International Journal of Pharmaceutics

Single vaccine dose produced lasting immune responses in mice

Antibody responses persisted for 165 days after one dose, while immune cells from the spleen showed responses at 180 days.Antibody responses persisted for 165 days after one dose, while immune cells from the spleen showed responses at 180 days.

Mouse study · 5 miceBlood and immune system
Cell Press Blue

Older human lymph nodes show signs of immune cell dysfunction

An observational study of lymph nodes from 51 donors aged 18–86 mapped age-linked changes in immune cells within regions involved in antibody responses.An observational study of lymph nodes from 51 donors aged 18–86 mapped age-linked changes in immune cells within regions involved in antibody responses.

Cross-sectional · 51 peopleBlood and immune system

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