Acute colitis

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Interventions

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Spermidine

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1 study

Spermidine protects against acute colitis in mice.
“spermidine exerted protective effects against acute colitis, evidenced by reduced disease activity index (DAI) and colonic inflammation”
AnimalsDSS- and TNBS-induced colitis
Preventive and Therapeutic Spermidine Treatment Attenuates Acute Colitis in Mice
Journal of agricultural and food chemistryFeb 4, 2021

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Probiotics reduce the severity of DSS-induced colitis in aged mice by enhancing intestinal barrier function and modulating gut microbiota

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Autophagy inhibitor 3-methyladenine mitigates the severity of colitis in aged mice by inhibiting autophagy

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Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice

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Aging and DiseaseDec 6

Tuberous Sclerosis Complex 1 Deficiency in Macrophages Promotes Unclassical Inflammatory Response to Lipopolysaccharide In Vitro and Dextran Sodium Sulfate-Induced Colitis in Mice

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Frontiers in ImmunologySep 8

Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis

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Green tea EGCG effectively alleviates experimental colitis in middle-aged male mice by attenuating multiple aspects of oxi-inflammatory stress and cell cycle deregulation

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International Journal of Molecular SciencesFeb 27

Novel Role of Ghrelin Receptor in Gut Dysbiosis and Experimental Colitis in Aging

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Influence of the microenvironment on modulation of the host response by typhoid toxin

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