BMC Public Health
Accumulated frailty linked to new depression in adults
Greater accumulated frailty was linked to higher odds of developing depression across four cohorts, with odds ratios ranging from 3.46 to 6.09.Greater accumulated frailty was linked to higher odds of developing depression across four cohorts, with odds ratios ranging from 3.46 to 6.09.

Cohort studyDepression
Who was studiedAdults aged ≥ 45 years
What changedNew depression was more likely with greater accumulated frailty (odds ratios 3.46–6.09 across cohorts)
The catchDifferent symptom scales across cohorts could classify depression unevenly



