Transposon expression

3 papers1 finding

Model organisms1
In silico2

Upstream

1

AGO2

downin flies1

1 study

AGO2 decreases transposon expression in flies.
“mutations in Drosophila Argonaute 2 (Ago2) resulted in exacerbated transposon expression in the brain”
Model organismsin Ago2 mutantsbrain
Activation of transposable elements during aging and neuronal decline in Drosophila
Nature neuroscience7 Apr 2013

Latest

eLife3 Apr

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence

Computational studyMechanisms

eLife18 Jan

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence

Preprint: computational studyCellular senescence

eLife22 Jun

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence

Preprint: computational studyCellular senescence

Genetics21 Apr

Expression of retrotransposons contributes to aging in Drosophila

Experiments in model organismsMechanisms

bioRxiv30 Dec

A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence

Preprint: computational studyCellular senescence

bioRxiv2 May

Dauer quiescence as well as continuity of the life cycle after dauer-exit in Caenorhabditis elegans are dependent on the endoribonuclease activity of XRN-2

Preprint: experiments in model organismsMechanisms

Nature Neuroscience7 Apr

Activation of transposable elements during aging and neuronal decline in Drosophila

Experiments in fliesTransposable element activity