Intron retention
1 paper1 finding
Upstream
1Aging transcriptomes
upin reviews1
1 study
Aging transcriptomes
upin reviews1
Aging transcriptomes increase intron retention.
“Aging transcriptomes show widespread disruption of RNA processing, including increased intron retention, cryptic splice-site usage, and altered RNA quality control.”
Review
The splicing axis of aging: mechanisms and therapeutic opportunities
Trends in molecular medicine21 Sep 2026
Latest
4 in 12 monthsTrends in Molecular Medicine
The splicing axis of aging: mechanisms and therapeutic opportunities
ReviewRNA splicing
bioRxiv
Causally measuring aging and rejuvenation through transcriptomic damage
Preprint: computational studyBiomarkers
Reproduction
Dysregulation of alternative splicing patterns in the ovaries of reproductively aged mice
Experiments in miceRNA splicing
The Journals of Gerontology, Series A
Systematic identification of exercise-induced anti-aging processes involving intron retention
Computational studyInterventions
bioRxiv
Dysregulation of alternative splicing patterns in the ovaries of reproductively aged mice
Preprint: experiments in animalsMechanisms
Cell Reports
Circular RNAs exhibit exceptional stability in the aging brain and serve as reliable age and experience indicators
Experiments in model organismsMechanisms