Memory impairment

Disease2 papers

Humans2

Trial sponsors

AstraZeneca
Company1 trialPhase 127 people
Wake Forest University Health Sciences
1 trialPhase 3276 people
Region Stockholm
1 trialPhase 284 people
University of Queensland
1 trialPhase 228 people
University of Pennsylvania
1 trialPhase 220 people
Yale University
1 trialPhase 110 people

Funding

National Institute on AgingUS$1.1m2 grants since 2022

The role of sex in GABAergic-mediated, Alzheimer’s disease-related episodic memory impairments from mid to late life
National Institute on AgingUniversity of Southern CaliforniaUS$810.1k2022–2027
Delineating how epigenetic regulation of ACVR1C contributes to age and AD-related memory impairments in females and males
National Institute on AgingArizona State University-tempe CampusUS$249k2024–2028

Latest

45

Behavioural Brain ResearchAnimals28 Sep

Aging reduces basal cholinergic reserve, but the pattern of scopolamine-induced memory impairment remains comparable in rats

bioRxivAnimalsPreprint26 Sep

Cholinergic impairment in the dorsal motor nucleus of the vagus during experimental Alzheimer’s disease

Behavioural Brain ResearchAnimals26 Sep

Age-related emergence of behavioral deficits and amyloid pathology in the J20 mouse model of Alzheimer's disease

Journal of Alzheimer's DiseaseHumans18 Sep

Multi-omics integration of transcriptomics and metabolomics with machine learning uncovers novel risk factors for Alzheimer's disease

Alzheimer's disease

Geriatrics & Gerontology InternationalHumans17 Sep

Joint Effect of Subjective Memory Impairment and Physical Inactivity on Cognitive Impairment: A 2-Year Follow-Up Study Among the Elderly in a Korean Population-Based Cohort Study

Cognitive impairment

PLOS Digital HealthHumans15 Sep

Reliable detection and continuous monitoring of memory dysfunction in mild cognitive impairment and healthy aging through adaptive computational phenotyping

Mild cognitive impairment

Frontiers in PsychologyHumans15 Sep

Obstructive sleep apnea risk is associated with a diminished cognitive profile: findings from the Canadian longitudinal study on aging

Neurochemical ResearchAnimals6 Sep

Strain-Specific Cognitive and Neurobiological Vulnerabilities to Social Isolation in Late Middle-Aged Wistar, Wistar-Kyoto, and Spontaneously Hypertensive Rats

Research SquareAnimalsPreprint3 Sep

Recurrent Sleep Restriction During Aging Induces Early Recognition Memory Impairment, Neuroinflammation, and Blood–Brain Barrier Dysfunction in Female Wistar Rats

Research SquareHumansPreprint3 Sep

A Study on the Association Between the Course of Heart Failure and Cognitive Function in Older Adults: Based on Data from the 2011–2014 National Health and Nutrition Examination Survey