Transcriptomic aging acceleration

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Insular cortex

downin humans1

1 study
  1. Transcriptomic aging acceleration is associated with insular cortex in humans (t = -3.30, P = 0.001).

    “Neuroimaging analyses demonstrated that transcriptomic aging was associated with structural (t = -3.30, P = 0.001) and functional (t = 2.64, P = 0.009) alterations in the right insular cortex.”

    Humansstructural alterationright insular cortex

    Peripheral transcriptomic aging acceleration in major depressive disorder: the mediating role of insular cortex alterations

    Psychological medicine8 Jul 2026

Major depressive disorder

upin humans1

1 study
  1. Major depressive disorder is associated with transcriptomic aging acceleration in humans (t = 3.72, P < 0.001).

    “Participants with MDD exhibited significantly accelerated transcriptomic aging both before (t = 2.06, P = 0.040) and after adjusting for chronological age and sex (t = 3.72, P < 0.001).”

    Humansadjusted for chronological age and sexperipheral blood

    Peripheral transcriptomic aging acceleration in major depressive disorder: the mediating role of insular cortex alterations

    Psychological medicine8 Jul 2026

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