Transcriptional signatures of inflammation and metabolic dysregulation

Biomarker

1 paper1 finding

  • Cells1

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1

NADK

downin mice1

1 study
  1. NADK decreases transcriptional signatures of inflammation and metabolic dysregulation in mice.

    “hepatic SaNADK expression in aged male mice partially alleviates transcriptional signatures of inflammation and metabolic dysregulation.”

    Animalshepatic SaNADK expressionconstitutively activelivermales

    Linked metabolic disruptions halt division in human cells

    Nature metabolism14 Oct 2026

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Nature Metabolism

Linked metabolic disruptions halt division in human cells

An engineered bacterial enzyme reversed the growth arrest by expanding a pool of molecules used to build cellular components in human connective-tissue cells grown in the…An engineered bacterial enzyme reversed the growth arrest by expanding a pool of molecules used to build cellular components in human connective-tissue cells grown in the lab.

Experiments in human cellsInterventions