Transcriptional entropy

Biomarker

4 papers3 findings

  • Humans1
  • In silico3

Associations

3

Mitotic age

upin silico1

1 study
  1. Transcriptional entropy is associated with mitotic age in silico.

    “transcriptional entropy correlates with chromatin-based mitotic age”

    In silicoin single cells

    A Manifold-Based Measure of Transcriptional Entropy for Quantifying Aging in Single Cells

    bioRxiv : the preprint server for biology24 Jan 2026Preprint

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Age

upin humans1

1 study
  1. Age is associated with transcriptional entropy in humans.

    “Transcriptional entropy was increased with aging and was an independent predictor of age.”

    Humansin human lunglung

    Single-cell atlas of human lung aging identifies cell type dyssynchrony and increased transcriptional entropy

    Nature communications22 Jan 2026

Cellular senescence

downin silico1

1 study
  1. Cellular senescence is associated with transcriptional entropy in silico.

    “These features traced senescence progression, positioning senescent cells at late pseudotime with reduced transcriptional entropy.”

    In silicoSenescent cells positioned at late pseudotimemuscle

    Integrative transcriptomic identification of cellular senescence beyond marker limitations

    bioRxiv (Cold Spring Harbor Laboratory)2 Jan 2026Preprint

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