Thrombin-antithrombin complex

2 papers1 finding

Humans1
Animals1

Upstream

1

THBD

downin pig cells1

1 study

THBD decreases thrombin-antithrombin complex in pig cells.
“BM7G porcine vascular endothelial cells significantly reduced the binding of human antibodies, effectively inhibited complement-dependent cytotoxicity, and decreased the formation of thrombin-antithrombin (TAT) complexes.”
CellsBM7G genetically modified porcine vascular endothelial cellsvascular endothelial cell
Development of a BM7G(TKO/hCD46/hCD55/hTHBD/hEPCR) donor pig with endogenous promoter-driven transgenes for xenotransplantation
Frontiers in immunology23 Jun 2026

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