GGTA1
Gene4 papers3 findingsHGNC 4253NCBI Gene 2681Taxon 9606
- Animals1
- Cells1
Effects
2Complement-dependent cytotoxicity
downin human cells1downin monkey cells1
1 study
Complement-dependent cytotoxicity
downin human cells1downin monkey cells1
GGTA1 decreases complement-dependent cytotoxicity in monkey cells.
Cellsversus WT iPAECs
Evaluation of primate anti-pig xenoreactive immune responses using immortalized aortic endothelial cells from genetically modified pigs · Frontiers in immunology · 9 Sep 2026
GGTA1 decreases complement-dependent cytotoxicity in human cells.
Cellsversus WT iPAECs
Evaluation of primate anti-pig xenoreactive immune responses using immortalized aortic endothelial cells from genetically modified pigs · Frontiers in immunology · 9 Sep 2026
Corneal graft failure
downin pigs1
1 study
Corneal graft failure
downin pigs1
GGTA1 decreases corneal graft failure in pigs (>1 year).
Reviewin preclinical studiescornealonger than 1 year
The role of the alpha-gal antigen in corneal xenotransplant rejection: a review · Arquivos brasileiros de oftalmologia · 28 Aug 2026