Telomere length ratio

1. Chemical mixture decreases telomere length ratio in humans.

   “33 chemical mixtures exposure was significantly negatively associated with the TL ratio (follow-up/baseline)”

   Humansoccupational co-exposureleukocyten = 867

   Associations of co-exposure to metals and polycyclic aromatic hydrocarbons with aging biomarkers: insights from epidemiology and network toxicology

   Frontiers in public health·May 28, 2026

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1. Inflammation mediates telomere length ratio in humans.

   “oxidative stress and inflammation mediated the link of major individual pollutants as well as the chemical mixture to biological aging”

   Humansoccupational exposuren = 867

   Associations of co-exposure to metals and polycyclic aromatic hydrocarbons with aging biomarkers: insights from epidemiology and network toxicology

   Frontiers in public health·May 28, 2026

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1. Oxidative stress and ROS signaling mediates telomere length ratio in humans.

   “oxidative stress and inflammation mediated the link of major individual pollutants as well as the chemical mixture to biological aging”

   Humansoccupational exposuren = 867

   Associations of co-exposure to metals and polycyclic aromatic hydrocarbons with aging biomarkers: insights from epidemiology and network toxicology

   Frontiers in public health·May 28, 2026

More on Oxidative stress and ROS signaling

1. Obesity predicts telomere length ratio in humans (0.125 larger telomere length ratio (95% CI 0.048–0.202)).

   “Baseline overweight (25kg/m2≤body mass index [BMI]<30kg/m2) and obesity (BMI≥30kg/m2) status positively predicted telomere length 17 years later.”

   HumansBaseline BMI ≥30 kg/m2; compared with normal weight adults17 yearsn = 2,749

   Body weight status and telomere length in U.S. middle-aged and older adults

   Obesity research & clinical practice·Feb 16, 2016

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1. Overweight predicts telomere length ratio in humans (0.062 larger telomere length ratio (95% CI 0.016–0.109)).

   “Baseline overweight (25kg/m2≤body mass index [BMI]<30kg/m2) and obesity (BMI≥30kg/m2) status positively predicted telomere length 17 years later.”

   HumansBaseline BMI 25 to <30 kg/m2; compared with normal weight adults17 yearsn = 2,749

   Body weight status and telomere length in U.S. middle-aged and older adults

   Obesity research & clinical practice·Feb 16, 2016

More on Overweight