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TERT-CLPTM1LVARIANTS

Gene

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab
  • Humans1

Associations

1

Telomere length shortening

mixedin humans1

1 study

  1. TERT-CLPTM1LVARIANTS is associated with telomere length shortening in humans (TL decline interaction P = 0.012 for rs401681 and 0.035 for rs465498).

    “the rs401681 and rs465498 could modify the effect of 1-OHP on increasing TL decline”

    HumansModification of the PAH exposure association; pronounced in rs401681TT and rs465498CC carriersleukocyte4 yearsn = 1,243

    The interaction effects of polycyclic aromatic hydrocarbons exposure and TERT- CLPTM1L variants on longitudinal telomere length shortening: A prospective cohort study

    Environmental pollution (Barking, Essex : 1987)

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