Telomerase activation

Papers on telomerase activation

652 papers2 new in 30 days

Saturday, October 31

Cell Death DiscoveryOct 31

Redox Orchestration of organ regeneration

ReviewMechanisms

Saturday, October 10

Research SquareOct 10

Blood-cell telomerase delays premature aging in zebrafish

Boosting telomerase in blood-forming cells extended lifespan in immune-deficient zebrafish and partly restored gut health, operating without major changes in telomere…Boosting telomerase in blood-forming cells extended lifespan in immune-deficient zebrafish and partly restored gut health, operating without major changes in telomere length.

Rag1 deficiency drives premature intestinal degeneration.

Preprint: experiments in zebrafishTelomerase and telomere maintenance

Wednesday, September 30

Preprints.orgSep 30

Sonnerachromones A–C from Sonneratia Apetala Delay Aging and Extend Lifespan in Caenorhabditis elegans Associated with Modulation of Telomere–Telomerase-Related Pathways

Preprint: experiments in wormsInterventions

Saturday, September 26

Current Issues in Molecular BiologySep 26

Conditional Senescence and Longevity Mechanisms in Early-Branching Metazoans: Insights from Hydra

Evidence-based framework for negligible and conditional senescence in Hydra.

ReviewMechanisms

Wednesday, September 16

JMIR Research ProtocolsSep 16

Evaluation of Vamana and Virechana as Interventions to Decelerate the Aging Process in Healthy Adult Volunteers: Protocol for an Exploratory Single-Arm Clinical Trial

Summary of the methodology.

Trial protocolInterventions

Friday, September 11

Preprints.orgSep 11

Epitalon and Epithalamin in Regenerative and Longevity Medicine: Mechanisms, Evidence, and Translational Gaps

Preprint: reviewInterventions

Thursday, September 10

European Journal of PharmacologySep 10

Plant compound cycloastragenol extended lifespan in worms

Mean lifespan rose 30.64% at a concentration of 0.2 micromolar; treated worms also showed better movement and stress resistance.Mean lifespan rose 30.64% at a concentration of 0.2 micromolar; treated worms also showed better movement and stress resistance.

Worm studyInterventions

Thursday, September 3

Mechanisms of Ageing and DevelopmentSep 3

Metformin therapy increases leukocyte telomere length, telomerase activity, and longevity gene expression in Asian Indians with prediabetes: A 24-week participant-blind, outcome-assessor-blinded randomized controlled trial

Randomized trial in 127 peopleMetformin

Wednesday, September 2

Frontiers in Cell and Developmental BiologySep 2

Telomerase expression and activity in the immortal cnidarian Hydra

(A) Conserved motifs of Homo and Hydra TERT proteins.

Experiments in hydraTelomerase and telomere maintenance

Nature Reviews GeneticsSep 2

How telomere attrition protects against cancer

ReviewTelomerase and telomere maintenance

Wednesday, August 19

Journal of Visualized ExperimentsAug 19

Optimized Reverse Transfection Protocol for Telomerase mRNA Delivery to Early-Senescent Human Fibroblasts

Experiments in human cellsInterventions

Thursday, August 13

Archives of Gerontology and GeriatricsAug 13

Telomerase RNA component knockout is associated with iron accumulation and altered transferrin receptor 1 and ferroportin 1 expression in the liver and lung

Experiments in miceTelomerase and telomere maintenance

Wednesday, August 5

Journal of Molecular EndocrinologyAug 5

Diabetes compromises DNA damage repair and telomere maintenance in adipose tissue stromal cells, leading to cellular senescence

Experiments in mouse cellsTelomerase and telomere maintenance

Thursday, July 23

Frontiers in AgingJul 23

Aging and vaccines: impact of immunosenescence and inflammaging in vaccine response

ReviewImmune response

Preprints.orgJul 23

Telomeres of People Living with HIV Are Confronted with Multifactorial Jeopardy: Can Lifestyle Modifications Ameliorate?

Preprint: reviewInterventions

Saturday, July 18

Biochemical and Biophysical Research CommunicationsJul 18

Polystyrene nanoplastics are associated with telomere-associated alterations and senescence-related changes in intestinal epithelial cells involving PPARα-POT1 regulation

Experiments in pig cellsTelomerase and telomere maintenance

Sunday, July 5

ZenodoJul 5

Deriva Entropica nei Sistemi Biologici: Decodifica Ingegneristica del Decadimento Telomerico

Preprint: computational studyTelomerase and telomere maintenance

Tuesday, June 30

International Journal of Research in Ayurveda and PharmacyJun 30

RIDGING TIME AND FUNCTION: A COMPREHENSIVE REVIEW OF BIOLOGICAL AGE, GLOBAL IMPLICATIONS, AND THE REJUVENATING POTENTIAL OF AYURVEDA

ReviewInterventions

Friday, June 26

CytotechnologyJun 26

Establishment and characterization of hTERT-immortalized rat bone marrow mesenchymal stromal cells with preserved anti-colitis activity in a DSS-induced mouse model

Experiments in miceColitis

BiomoleculesJun 26

Astragalus membranaceus Has Potential Anti-Aging and Anticancer Effects on Skin and Bone

ReviewSkin

BiomedicinesJun 26

Reframing Telomere Biology in Exercise Science: From Descriptive Metrics to Redox-Metabolic Mechanisms for Precision Healthy Aging (2000-2025)

ReviewAerobic exercise

Tuesday, June 23

Molecular Biology ReportsJun 23

Telomere biology and telomerase regulation across species: evolutionary insights into aging, longevity, and genome stability

ReviewTelomerase and telomere maintenance

Tuesday, June 16

G3Jun 16

Alternative lengthening of telomeres is dependent on RAD52 and RAD51 gene function in the budding yeast Naumovozyma castellii

Experiments in cellsTelomerase and telomere maintenance

Thursday, June 11

Journal of NeuroendocrinologyJun 11

The aging paradox of Cushing's syndrome: Stress without clear senescence?

ReviewCellular senescence

Tuesday, June 9

INTERNATIONAL BLEST SCIENTIFICJun 9

PEPTIDE BIOREGULATORS, AGING AND HUMAN LONGEVITY: EPITHALON, THYMALIN, THYMOGEN, DSIP, VILON AND VESUGEN IN CIRCADIAN BIOLOGY, TELOMERASE REGULATION AND INFLAMMAGING

ReviewInterventions

Tuesday, June 2

Journal of Pharmaceutical Research and Integrated Medical SciencesJun 2

Modulating The Epigenetic Clock, Senolytic Therapies for Human Longevity: Age Tissue Regeneration, Synergistic Effect of Nad+ Precursors and Telomerase, Human Age Enhancement

ReviewNAD+ precursors

Sunday, May 31

Turkish Journal of Clinical ResearchMay 31

The telomere paradox: Dual regulatory roles in aging and cancer

ReviewTelomerase and telomere maintenance

Wednesday, May 27

BiomedicinesMay 27

Genetic Determinants of Telomere Length and Their Role in Human Disease: Molecular Mechanisms and Underrepresented Populations' Perspectives

ReviewTelomerase and telomere maintenance

Monday, May 25

Preprints.orgMay 25

Telomere Dysfunction and Extracellular Matrix Remodeling

Preprint: reviewTelomerase and telomere maintenance

Thursday, May 21

International Journal of Social Science and Human ResearchMay 21

The Bio-Social Pathology of Modern Urban Life: Loneliness, Social Isolation and Telomere Shortening

ReviewTelomerase and telomere maintenance