1 paper
Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best predicted dementia risk.Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best predicted dementia risk.
Four patterns captured most variation in connections across 438 brain regions and were reproducible across repeated scans and independent datasets.Four patterns captured most variation in connections across 438 brain regions and were reproducible across repeated scans and independent datasets.
In 3,650 adults, elevated modeled dopamine clearance was linked to poorer cognition only with marked structural degradation and within sliding age windows centered…In 3,650 adults, elevated modeled dopamine clearance was linked to poorer cognition only with marked structural degradation and within sliding age windows centered between 56 and 76 years.