Alzheimer's disease symptom onset

1. Accelerated long-term forgetting predicts Alzheimer's disease symptom onset in humans (AUC=0.82 (story), AUC=0.73 (list)).

   “Story ALF (AUC=0.82) and list ALF (AUC=0.73) discriminated between those who did and did not develop symptoms.”

   Humanspredicting symptom onset in mutation carriersmedian 7 years

   Neuroimaging correlates and prognostic utility of accelerated long‐term forgetting in presymptomatic autosomal dominant Alzheimer's disease

   AAIC 2025 abstract·25 Dec 2025

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