Striatal dopamine

Papers on striatal dopamine

71 papers3 new in 30 days

Wednesday, November 11

bioRxiv

Dopamine availability peaked in adulthood in primates and rodents

Lifespan measurements in primates and rodents also found age-dependent differences in how two signaling chemicals regulated dopamine release.Lifespan measurements in primates and rodents also found age-dependent differences in how two signaling chemicals regulated dopamine release.

Branching nerve fibers have dense dopamine specks near an adult macaque and sparse specks near younger and older macaques, with nerve cells around them.
Preprint: animal studyMechanisms

Friday, November 6

bioRxiv

Brain chemistry and protein buildup linked to network changes

Brain scans linked dopamine production capacity and Alzheimer’s-related protein buildup to distinct patterns of network organization in young and cognitively unimpaired…Brain scans linked dopamine production capacity and Alzheimer’s-related protein buildup to distinct patterns of network organization in young and cognitively unimpaired older adults.

Brain sections show separated regions with branching neurons beside crowded regions containing gray protein deposits and dark tangles.
Preprint: cross-sectional studyMechanisms

Monday, November 2

Saturday, September 19

Friday, July 17

Monday, June 29

Research Square

Supplement improved movement in mice modeling Parkinson’s disease

Male and female mice received nicotinamide riboside in drinking water for 21 weeks, improving movement without preventing the loss of dopamine-producing brain cells.Male and female mice received nicotinamide riboside in drinking water for 21 weeks, improving movement without preventing the loss of dopamine-producing brain cells.

Preprint: mouse studyParkinson's disease

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