Soluble α-klotho

1. Age decreases soluble α-klotho in humans.

   “salphaKl correlated negatively with age and Ca, and positively with Pi.”

   Humanshealthy subjects

   Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects

   Biochemical and biophysical research communications·1 Jul 2010

1. Alcohol is associated with soluble α-klotho in humans (β=-17.031, R2 = 0.096, P = 0.013).

   “Total alcoholic drinks consumption was negatively associated with S-Klotho plasma levels (β=-17.031; R2 = 0.096, P = 0.013).”

   Humanssedentary healthyplasman = 74

   Alcohol consumption and S-Klotho plasma levels in sedentary healthy middle-aged adults: A cross sectional study

   Drug and alcohol dependence·3 Nov 2018

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