Social frailty

1. Social frailty predicts amyloid-beta 42 in C. aethiops (t=-2.345).

   “lower Ab42 (t=‐2.345 p = 0.022) and Ab40 (t=‐2.138, p = 0.036).”

   Animalsat approximately one year follow-upfemales

   Social frailty and brain health in nonhuman primates: Relationships between social behavior, neuroanatomy, and CSF biomarkers relevant to Alzheimer's disease · AAIC 2025 abstract · 8 Jan 2026

Amyloid-beta 42 →

1. Social frailty predicts phosphorylated tau in C. aethiops (t=2.304).

   “Higer social frailty predicted higher levels of phosphorylated tau (t=2.304, p = 0.024)”

   Animalsat approximately one year follow-upfemales

   Social frailty and brain health in nonhuman primates: Relationships between social behavior, neuroanatomy, and CSF biomarkers relevant to Alzheimer's disease · AAIC 2025 abstract · 8 Jan 2026

Phosphorylated tau →