Serum phosphate

1. Magnesium decreases serum phosphate in humans.

   “Mg supplementation may help reduce serum phosphate concentration, PTH, and interfere with vascular calcification and bone mineralization.”

   Reviewin dialyzed patients

   Magnesium supplementation: A consideration in dialysis patients

   Seminars in dialysis·Oct 23, 2017

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1. Calcium alpha-ketoglutarate decreases serum phosphate in humans (from 2.6 +/- 0.1 to 1.9 +/- 0.07 mmol/l (p < 0.001)).

   “Serum P continuously dropped from prestudy 2.6 +/- 0.1 (mean +/- SEM) to 1.9 +/- 0.07 mmol/l (p < 0.001)”

   Human trialhemodialysis patientssoluble preparation4.5 g/day36 monthsn = 14

   Long-term treatment with calcium-alpha-ketoglutarate corrects secondary hyperparathyroidism

   Mineral and electrolyte metabolism·Jan 1, 1996

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1. Serum phosphate is associated with biological age in humans.

   “Accelerated ageing is associated with high serum Pi levels and frequency of red meat consumption.”

   Humansn = 666

   Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake

   Aging·May 1, 2016