Second-generation epigenetic clocks

4 papers1 finding

Humans3

Associations

1

Morbidity and mortality

mixedin humans1

1 study

Second-generation epigenetic clocks predict morbidity and mortality in humans.
“This review provides a survey of these clocks, with an emphasis on second-generation clocks that predict human morbidity and mortality.”
Review
Quantification of Epigenetic Aging in Public Health
Annual review of public health16 Dec 2024

Latest

12 in 12 months

Research Square6 Oct

Low back pain, disability, and biological aging: routinely measurable clinical clocks versus epigenetic clocks (NHANES)

Preprint: cross-sectional study of 2,532 peopleLow back pain

Psychoneuroendocrinology22 Sep

Nativity and epigenetic age acceleration among Hispanics/Latinos in the Hispanic Community Health Study/Study of Latinosl (HCHS/SOL)

Cohort study of 961 peoplePopulations

medRxiv9 Sep

Childhood trauma, accelerated biological aging and chronic pain across two population cohorts

Preprint: cohort study of 1,041 peopleChronic pain

The Journal of Prevention of Alzheimer's Disease7 Aug

Psychological adversities and epigenetic ageing in midlife and older age: A systematic review and meta-analysis

Meta-analysis of observational studiesPopulations

Clinical Epigenetics8 Jul

Exploring a targeted epigenetic clock based on mortality-associated CpGs as a potential biomarker for frailty

Cohort study of 446 peopleEpigenetic clock

GeroScience21 Jun

Analysis of second-generation epigenetic clocks reveals further associations between disproportionate biological ageing and hippocampal volume

Study in peopleBiomarkers

medRxiv7 May

Neighborhood Deprivation Is Associated with Accelerated Epigenetic Aging Via Greater Individual Adversity

Preprint: study in peoplePopulations

EClinicalMedicine23 Apr

Metformin and epigenetic age in non-diabetic older people with HIV in Madrid (METFORAGING): a double-blind, randomised, placebo-controlled, pilot trial

Randomised trial in 40 peopleMetformin

Current HIV/AIDS Reports29 Mar

Epigenetic aging is a hallmark of HIV pathogenesis and phenotypic outcomes

ReviewBiomarkers

Nature Medicine10 Mar

Effects of daily multivitamin-multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial

Randomised trial in 958 peopleInterventions